Disdier P, Harle J R, Grob J J, Weiller-Merli C, Magalon G, Weiller P J
Service de Médecine Interne du Prof. P.J. Weiller, Clinique Médicale B, Hôpital de La Timone, France.
Dermatologica. 1991;183(1):47-8. doi: 10.1159/000247631.
We report a 65-year-old patient who presented a rapid eruption of keratoses on sun-exposed areas and an explosive transformation into several squamous-cell carcinomas, occurring during the accelerated phase of a chronic granulocytic leukemia. Clinical findings resembled those usually described in xeroderma pigmentosum. The role of immunosuppression, chemotherapy and possible genetic predisposition is discussed.
我们报告了一名65岁的患者，在慢性粒细胞白血病加速期，其暴露于阳光下的部位迅速出现角化病，并迅速转变为多个鳞状细胞癌。临床症状与通常在着色性干皮病中描述的症状相似。文中讨论了免疫抑制、化疗以及可能的遗传易感性所起的作用。
