Rapid development of multiple squamous-cell carcinomas during chronic granulocytic leukemia.

作者信息

Disdier P, Harle J R, Grob J J, Weiller-Merli C, Magalon G, Weiller P J

机构信息

Service de Médecine Interne du Prof. P.J. Weiller, Clinique Médicale B, Hôpital de La Timone, France.

出版信息

Dermatologica. 1991;183(1):47-8. doi: 10.1159/000247631.

We report a 65-year-old patient who presented a rapid eruption of keratoses on sun-exposed areas and an explosive transformation into several squamous-cell carcinomas, occurring during the accelerated phase of a chronic granulocytic leukemia. Clinical findings resembled those usually described in xeroderma pigmentosum. The role of immunosuppression, chemotherapy and possible genetic predisposition is discussed.