Matanović K, Severin K, Martinković F, Simpraga M, Janicki Z, Barisić J
Department of Physiology and Radiobiology, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000 Zagreb, Croatia.
Parasitol Res. 2007 Nov;101(6):1657-61. doi: 10.1007/s00436-007-0709-2. Epub 2007 Aug 13.
A naturally occurring outbreak of fasciolosis in a group of 20 Merinolandschaf (German Merino) sheep was studied. Hematological and blood biochemical values in sheep spontaneously infected with liver fluke Fasciola hepatica were compared with equivalent values in 20 parasite-free sheep from organically farmed flock. Investigated animals were kept in outdoor system, on pastures covered with swamps, which remain flooded after rainy season. Significantly lower red blood cell (RBC) count, lymphocytes, hemoglobin (Hb), packed cell volume (PCV), mean corpuscular hemoglobin concentration (MCHC), aspartate aminotransferase (AST), blood urea nitrogen (BUN), creatinine, and albumin were recorded in sheep from the infected herd, whereas white blood cell (WBC) count, eosinophil, segmented and band neutrophil count, mean corpuscular volume (MCV), gamma-glutamyl transferase (GGT), concentrations of glucose, and globulins were significantly higher than in the parasite free herd. No significant correlation between the investigated blood parameters and the number of F. hepatica eggs in the feces was detected. This study shows that hematological and biochemical values can be useful in early diagnosis and prognosis of sheep fasciolosis.
对一群20只美利奴山（德国美利奴）绵羊自然发生的肝片吸虫病疫情进行了研究。将自然感染肝片吸虫的绵羊的血液学和血液生化值与来自有机养殖羊群的20只无寄生虫绵羊的相应值进行了比较。被调查的动物饲养在户外系统中，在雨季过后仍被水淹没的沼泽覆盖的牧场上。感染羊群的绵羊红细胞（RBC）计数、淋巴细胞、血红蛋白（Hb）、血细胞比容（PCV）、平均红细胞血红蛋白浓度（MCHC）、天冬氨酸转氨酶（AST）、血尿素氮（BUN）、肌酐和白蛋白显著降低，而白细胞（WBC）计数、嗜酸性粒细胞、分叶和杆状中性粒细胞计数、平均红细胞体积（MCV）、γ-谷氨酰转移酶（GGT）、葡萄糖浓度和球蛋白显著高于无寄生虫羊群。未检测到所调查的血液参数与粪便中肝片吸虫卵数量之间的显著相关性。这项研究表明，血液学和生化值可用于绵羊肝片吸虫病的早期诊断和预后。
