类风湿性滑膜组织培养基对人白细胞原胶原酶的激活作用。
Activation of human leucocyte procollagenase by rheumatoid synovial tissue culture medium.
作者信息
Wize J, Abgarowicz T, Wojtecka-Lukasik E, Ksiezny S, Dancewicz A M
出版信息
Ann Rheum Dis. 1975 Dec;34(6):520-3. doi: 10.1136/ard.34.6.520.
Abstract
Production of a factor activating leucocyte procollagenase by tissue culture of rheumatoid synovium was shown. The activator was isolated, partly purified, and shown to be thermolabile, nondialysable, and had no activity toward casein, haemoglobin, histones, and PZ-peptide. The activity of the activator was partly decreased by trypsin.
摘要
通过类风湿性滑膜炎组织培养显示出可产生一种激活白细胞原胶原酶的因子。该激活剂被分离、部分纯化，并显示出对热不稳定、不可透析，且对酪蛋白、血红蛋白、组蛋白和PZ肽无活性。胰蛋白酶可部分降低该激活剂的活性。
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