Fedorenko V I
Gig Sanit. 1991 Jun(6):62-3.
The appearance of the toxicity phenomenon in the mixture with the simultaneous analysis of the characters of the combined actions of the elements were studied in experiments using as a model incredop composition to determine the significance of each components and quantitative interactions. It was found, that elimination from this mixture even of a single element or changing in the quantitative interactions between elements caused the changes in the toxicity, levels of the sumulation and characters of the combined actions of the components. Therefore the mixtures must be studied as the single object with the establishment of according standards which may not correlate with that in the individual compounds.
在使用一种复杂成分作为模型的实验中，研究了混合物中毒性现象的出现以及元素联合作用特征的同时分析，以确定每种成分的重要性和定量相互作用。研究发现，从该混合物中去除哪怕一种元素或改变元素之间的定量相互作用，都会导致毒性、累积水平以及成分联合作用特征的变化。因此，必须将混合物作为一个单一对象进行研究，并建立相应的标准，这些标准可能与单个化合物中的标准不相关。
