[Hygienic evaluation of hazardous materials].

The appearance of the toxicity phenomenon in the mixture with the simultaneous analysis of the characters of the combined actions of the elements were studied in experiments using as a model incredop composition to determine the significance of each components and quantitative interactions. It was found, that elimination from this mixture even of a single element or changing in the quantitative interactions between elements caused the changes in the toxicity, levels of the sumulation and characters of the combined actions of the components. Therefore the mixtures must be studied as the single object with the establishment of according standards which may not correlate with that in the individual compounds.