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韩国猪圆环病毒2型的基因特征分析

Genetic characterization of porcine circovirus type 2 in Republic of Korea.

作者信息

Choi Kyoung-Seong, Chae Joon-Seok

机构信息

Department of Animal Science, College of Life Science and Natural Resources, Sangju National University, 386 Gajang-Dong, Sangju 742-711, Republic of Korea.

出版信息

Res Vet Sci. 2008 Jun;84(3):497-501. doi: 10.1016/j.rvsc.2007.05.017. Epub 2007 Aug 14.

Abstract

Porcine circovirus type 2 (PCV2) is a major causative agent of postweaning multisystemic wasting syndrome (PMWS). Sequence and phylogenetic analyses based on the ORF2 capsid protein gene fragment showed that field isolate in Republic of Korea (ROK), PCV2 YJK 0703, was closely related with the PCV2 Fh18 isolate. PCV2 YJK 0703 was genetically distinct and not related to previously reported ROK isolates. Therefore, genotypic variation exists among prevailing PCV2 in ROK. This result suggests that several PCV2 genotypes exist in Korean pig farms.

摘要

猪圆环病毒2型(PCV2)是断奶后多系统消耗综合征(PMWS)的主要致病因子。基于开放阅读框2(ORF2)衣壳蛋白基因片段的序列和系统发育分析表明,韩国的田间分离株PCV2 YJK 0703与PCV2 Fh18分离株密切相关。PCV2 YJK 0703在基因上是独特的,与先前报道的韩国分离株无关。因此,韩国流行的PCV2之间存在基因型变异。这一结果表明,韩国猪场存在几种PCV2基因型。

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