Three new steroids from the roots of Serratula wolffii.

作者信息

Simon András, Tóth Gábor, Liktor-Busa Erika, Kele Zoltán, Takács Mária, Gergely András, Báthori Mária

机构信息

Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szt Gellért tér 4, H-1111, Budapest, Hungary.

出版信息

Steroids. 2007 Oct;72(11-12):751-5. doi: 10.1016/j.steroids.2007.06.004. Epub 2007 Jul 6.

DOI:10.1016/j.steroids.2007.06.004

PMID:17698156

Abstract

Investigation of the methanol extract of the roots of Serratula wolffii resulted in an ecdysone-related compound, 2beta,3beta,20R,22R,25-pentahydroxy-5beta-cholest-6,8(14)-dien (1), a new ecdysteroid, 24-methylene-shidasterone (2), the known compound stachysterone B (3) and its 14,15-alpha-epoxide (4), a novel natural product. The structures of compounds 1-4 were established by spectral analysis ((1)H NMR, (13)C NMR, COSY, NOESY, HMQC, HMQC-TOCSY and HMBC).

摘要