Spector G J, Druck N S, Gado M
Arch Neurol. 1976 Apr;33(4):270-4. doi: 10.1001/archneur.1976.00500040054008.
In 75 patients with glomus tumors in the head and neck region, 57 tumors arose from the jugular bulb region, 11 from the middle ear, and seven from the vagus nerve. Thirty-seven percent (28 patients) had cranial nerve paralysis, and 14.6% (11) had intracranial tumor extension. The jugular foramen syndrome was associated with a 50% (two of four patients) incidence, and hypoglossal nerve paralysis with a 75% (three of four) incidence of posterior fossa tumor invasion. Horner syndrome and labyrinthine destruction had a 50% (two of four) incidence of a middle cranial fossa tumor invasion. The incidence of central nervous system (CNS) invasion with cranial nerve paralysis (excluding the seventh nerve) was 52% (11 of 21). Otologic findings and seventh nerve paralysis did not correlate with CNS tumor extension.
在75例头颈部球瘤患者中,57例肿瘤起源于颈静脉球区域,11例起源于中耳,7例起源于迷走神经。37%(28例患者)出现颅神经麻痹,14.6%(11例)出现颅内肿瘤扩展。颈静脉孔综合征的发生率为50%(4例患者中的2例),舌下神经麻痹伴后颅窝肿瘤侵犯的发生率为75%(4例中的3例)。霍纳综合征和迷路破坏伴中颅窝肿瘤侵犯的发生率为50%(4例中的2例)。伴有颅神经麻痹(不包括第七神经)的中枢神经系统(CNS)侵犯发生率为52%(21例中的11例)。耳科检查结果和第七神经麻痹与CNS肿瘤扩展无关。