Khalid Saifullah, Zaheer Samreen, Khalid Mohd, Zaheer Sufian, Raghuwanshi Raj Kumar
Dr. Saifullah Khalid, SR, Department of Radiodiagnosis,, Jawaharlal Nehru Medical College & Hospital;, House No. 386-A, Street No.1, Iqra Colony,, Aligarh, Uttar Pradesh-202002 India, M: 0091-9897218098,
Ann Saudi Med. 2013 Jul-Aug;33(4):407-10. doi: 10.5144/0256-4947.2013.407.
Collet-Sicard syndrome is caused by various neoplastic and non-neoplastic lesions affecting the base of the skull with involvement of IX, X, XI and XII cranial nerves. Paraganglioma accounts for < 1% of all the neoplasms in the head and neck region. They are traditionally considered as benign, slow growing, locally invasive, encapsulated and highly vascular tumors. We report a case of Collet-Sicard syndrome secondary to a large glomus jugulotympanicum in a 45-year-old woman who presented to the emergency department with complaints of recurrent episodes of a fresh bleeding from the left ear for the previous 5 days. She had pain and decreased hearing for the last 3 years and features of multiple cranial nerve palsies. A radiological diagnosis of glomus jugulotympanicum (paraganglioma) was made, which was confirmed by the biopsy tissue. At 6-month follow up, episodes of recurrent bleeding had stopped, but cranial nerve palsies persisted.
科莱-西卡尔综合征是由各种影响颅底并累及Ⅸ、Ⅹ、Ⅺ和Ⅻ颅神经的肿瘤性和非肿瘤性病变引起的。副神经节瘤在头颈部所有肿瘤中占比不到1%。它们传统上被认为是良性、生长缓慢、局部浸润、有包膜且血管丰富的肿瘤。我们报告一例45岁女性因巨大颈静脉鼓室球瘤继发科莱-西卡尔综合征,该患者因左耳反复新鲜出血5天前来急诊科就诊。她在过去3年中有疼痛和听力下降,并有多组颅神经麻痹的症状。经放射学诊断为颈静脉鼓室球瘤(副神经节瘤),活检组织证实了这一诊断。在6个月的随访中,反复出血的情况已停止,但颅神经麻痹仍然存在。