科罗拉多州自由放养的骡鹿中与绵羊疱疹病毒-2相关的恶性卡他热

Malignant catarrhal fever associated with ovine herpesvirus-2 in free-ranging mule deer in Colorado.

作者信息

Schultheiss Patricia C, Van Campen Hana, Spraker Terry R, Bishop Chad, Wolfe Lisa, Podell Brendan

机构信息

Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA.

出版信息

J Wildl Dis. 2007 Jul;43(3):533-7. doi: 10.7589/0090-3558-43.3.533.

DOI:10.7589/0090-3558-43.3.533

PMID:17699095

Abstract

Malignant catarrhal fever (MCF) was diagnosed in four free-ranging mule deer (Odocoileus hemionus) in January and February of 2003. Diagnosis was based on typical histologic lesions of lymphocytic vasculitis and PCR identification of ovine herpesvirus-2 (OHV-2) viral genetic sequences in formalin-fixed tissues. The animals were from the Uncompahgre Plateau of southwestern Colorado. Deer from these herds occasionally resided in close proximity to domestic sheep (Ovis aries), the reservoir host of OHV-2, in agricultural valleys adjacent to their winter range. These cases indicate that fatal OHV-2 associated MCF can occur in free-ranging mule deer exposed to domestic sheep that overlap their range.

摘要

2003年1月和2月，在4只自由放养的骡鹿（白尾鹿）身上诊断出恶性卡他热（MCF）。诊断依据是淋巴细胞性血管炎的典型组织学病变以及在福尔马林固定组织中通过聚合酶链反应（PCR）鉴定出绵羊疱疹病毒2型（OHV-2）的病毒基因序列。这些动物来自科罗拉多州西南部的昂卡帕格雷高原。这些鹿群中的鹿偶尔会在其冬季活动范围附近的农业山谷中，与OHV-2的储存宿主家养绵羊（ovis aries）近距离生活。这些病例表明，接触到与其活动范围重叠的家养绵羊的自由放养骡鹿可能会感染致命的与OHV-2相关的MCF。