Rukosujew Andreas, Klotz Stefan, Reitz Christiane, Gogarten Wiebke, Welp Henryk, Scheld Hans H
Department of Thoracic and Cardiovascular Surgery, University Hospital Muenster, Albert-Schweitzer-Str. 33, D-48129 Muenster, Germany.
Interact Cardiovasc Thorac Surg. 2007 Dec;6(6):768-71. doi: 10.1510/icvts.2007.152884. Epub 2007 Aug 15.
Off-pump operations (OPCAB) are growingly used for patients with coronary artery disease (CAD) and may be associated with improved outcomes when compared with coronary artery bypass grafting (CABG) using extracorporeal circulation (ECC), especially in patients with comorbidities. The aim of this study is to compare the intra- and postoperative results of OPCAB complete arterial myocardial revascularization with standard on-pump CABG under respect of comorbidities.
We report about the implementing of the off-pump technique in our institution from November 2004 to May 2006. Sixty-two patients with CABG in off-pump technique were compared to a control group of 129 patients with CABG using ECC. The off-pump technique was mostly used in patients with vascular and pulmonary diseases. All operations were performed by the same surgeon. All off-pumps were performed using both internal thoracic arteries (ITA) or left ITA and radial artery (RA) in T-graft technique, while in the on-pump group only the LITA and saphenous vein were used. The conversion rate from OPCAB to conventional CABG was 3.2% (two patients).
Peripheral vascular disease (PVD) and chronic obstructive pulmonary disease (COPD) were significant more often in the off-pump group. Other preoperative risk factors were comparable between the groups. Operation time was significantly longer in the off-pump group. Postoperative symptomatic transient psychotic syndromes were more often in the on-pump group. Outcome was similar, despite significant longer operation time in off-pump group.
Off-pump coronary artery surgery can be performed in patients with comorbidities with similar outcome compared to on-pump surgery.
非体外循环手术(OPCAB)越来越多地用于冠状动脉疾病(CAD)患者,与使用体外循环(ECC)的冠状动脉旁路移植术(CABG)相比,可能会带来更好的治疗效果,尤其是在合并症患者中。本研究的目的是在考虑合并症的情况下,比较非体外循环完全动脉心肌血运重建术与标准体外循环CABG的术中和术后结果。
我们报告了2004年11月至2006年5月期间我院非体外循环技术的实施情况。将62例行非体外循环技术CABG的患者与129例行体外循环CABG的对照组患者进行比较。非体外循环技术主要用于血管和肺部疾病患者。所有手术均由同一位外科医生进行。所有非体外循环手术均采用双侧胸廓内动脉(ITA)或左ITA和桡动脉(RA)行T型移植技术,而体外循环组仅使用左内乳动脉(LITA)和大隐静脉。非体外循环冠状动脉搭桥术转为传统冠状动脉搭桥术的转化率为3.2%(2例患者)。
非体外循环组外周血管疾病(PVD)和慢性阻塞性肺疾病(COPD)的发生率明显更高。两组之间的其他术前危险因素相当。非体外循环组的手术时间明显更长。体外循环组术后症状性短暂性精神综合征更为常见。尽管非体外循环组手术时间明显更长,但结果相似。
合并症患者行非体外循环冠状动脉手术与体外循环手术的结果相似。