Luijsterburg Pim A J, Lamers Leida M, Verhagen Arianne P, Ostelo Raymond W J G, van den Hoogen Hans J M M, Peul Wilco C, Avezaat Cees J J, Koes Bart W
Department of General Practice, Erasmus Medical Center, Rotterdam, The Netherlands.
Spine (Phila Pa 1976). 2007 Aug 15;32(18):1942-8. doi: 10.1097/BRS.0b013e31813162f9.
An economic evaluation alongside a randomized clinical trial in primary care. A total of 135 patients were randomly allocated to physical therapy added to general practitioners' care (n = 67) or to general practitioners' care alone (n = 68).
To evaluate the cost-effectiveness of physical therapy and general practitioner care for patients with an acute lumbosacral radicular syndrome (LRS, also called sciatica) compared with general practitioner care only.
There is a lack of knowledge concerning the cost-effectiveness of physical therapy in patients with sciatica.
The clinical outcomes were global perceived effect and quality of life. The direct and indirect costs were measured by means of questionnaires. The follow-up period was 1 year. The Incremental Cost-effectiveness Ratio (ICER) between both study arms was constructed. Confidence intervals for the ICER were calculated using Fieller's method and using bootstrapping.
There was a significant difference on perceived recovery at 1-year follow-up in favor of the physical therapy group. The additional physical therapy did not have an incremental effect on quality of life. At 1-year follow-up, the ICER for the total costs was 6224 euros (95% confidence interval, -10,419, 27,551) per improved patient gained. For direct costs only, the ICER was 837 euros (95% confidence interval, -731, 3186).
The treatment of patients with LRS with physical therapy and general practitioners'care is not more cost-effective than general practitioners'care alone.
一项与初级保健中的随机临床试验同步进行的经济学评估。总共135名患者被随机分配至在全科医生护理基础上增加物理治疗组(n = 67)或仅接受全科医生护理组(n = 68)。
评估与仅接受全科医生护理相比,物理治疗与全科医生护理联合治疗急性腰骶神经根综合征(LRS,也称为坐骨神经痛)患者的成本效益。
对于坐骨神经痛患者物理治疗的成本效益缺乏了解。
临床结局为总体感知效果和生活质量。通过问卷调查测量直接和间接成本。随访期为1年。构建两个研究组之间的增量成本效益比(ICER)。使用Fieller方法和自助法计算ICER的置信区间。
在1年随访时,在感知恢复方面存在显著差异,物理治疗组更具优势。额外的物理治疗对生活质量没有增量影响。在1年随访时,每获得1例病情改善患者的总成本ICER为6224欧元(95%置信区间,-10419, 27551)。仅对于直接成本,ICER为837欧元(95%置信区间,-731, 3186)。
对于LRS患者而言,物理治疗与全科医生护理联合治疗并不比单纯全科医生护理更具成本效益。