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先天性心脏病胸骨切开术后脊柱畸形发展的回顾性研究。

Retrospective study on the development of spinal deformities following sternotomy for congenital heart disease.

作者信息

Herrera-Soto José A, Vander Have Kelly L, Barry-Lane Patricia, Myers John L

机构信息

Pediatric Orthopedic Department, Orlando Regional Medical Center, Orlando, FL, USA.

出版信息

Spine (Phila Pa 1976). 2007 Aug 15;32(18):1998-2004. doi: 10.1097/BRS.0b013e318131b225.

Abstract

STUDY DESIGN

Retrospective review with a minimum of 3 years of follow-up.

OBJECTIVE

We hypothesize that following median sternotomy there may be an increase incidence of both sagittal and coronal spinal deformity. We also think that heart size and a cyanotic cardiac condition are also risk factors for development of spinal deformity. The purpose of this study was to determine the incidence and characteristics of spinal deformity in patients following sternotomy for congenital heart disease.

SUMMARY OF BACKGROUND DATA

Patients with congenital heart disease are at an increased risk to develop scoliosis.

METHODS

A total of 108 patients underwent a median sternotomy for the treatment of congenital heart disease and met inclusion criteria. The medical record was reviewed to gather demographic data and medical and surgical history. Serial chest and spine radiographs were reviewed.

RESULTS

Scoliosis developed in 28% of the patients (10 males, 20 females). The mean follow-up was 13 years (range, 3-26 years). The mean coronal Cobb angle was 25 degrees (range, 11 degrees-88 degrees). Of these, 7 patients presented with curves of > or = 30 degrees. The mean age at diagnosis of scoliosis was 14 years (range, 2-33 years). A kyphotic deformity developed in 22% (24 patients). In patients with scoliosis, the mean sagittal kyphosis was 34 degrees (range, 2 degrees-73 degrees). Patients with a cyanotic cardiac condition had a trend toward severe scoliosis. There was no correlation between the development of scoliosis or kyphosis and the age at time of procedures, number of surgeries, gender, or heart size.

CONCLUSION

The risk of developing scoliosis in children with congenital heart disease is more than 10 times that of idiopathic scoliosis. Spinal deformities, including scoliosis and/or kyphosis, were found in 34% of the patients. The sagittal alignment in scoliosis patients tends toward kyphosis.

摘要

研究设计

进行至少3年随访的回顾性研究。

目的

我们假设在正中胸骨切开术后,矢状面和冠状面脊柱畸形的发生率可能会增加。我们还认为心脏大小和青紫型心脏病也是脊柱畸形发展的危险因素。本研究的目的是确定先天性心脏病患者胸骨切开术后脊柱畸形的发生率和特征。

背景数据总结

先天性心脏病患者发生脊柱侧弯的风险增加。

方法

共有108例患者接受了正中胸骨切开术治疗先天性心脏病并符合纳入标准。查阅病历以收集人口统计学数据以及医疗和手术史。回顾系列胸部和脊柱X线片。

结果

28%的患者(10例男性,20例女性)发生了脊柱侧弯。平均随访时间为13年(范围3 - 26年)。平均冠状面Cobb角为25度(范围11度 - 88度)。其中,7例患者的侧弯角度≥30度。脊柱侧弯诊断时的平均年龄为14岁(范围2 - 33岁)。22%(24例患者)出现了后凸畸形。在脊柱侧弯患者中,矢状面平均后凸为34度(范围2度 - 73度)。青紫型心脏病患者有发生严重脊柱侧弯的趋势。脊柱侧弯或后凸的发生与手术时年龄、手术次数、性别或心脏大小之间无相关性。

结论

先天性心脏病患儿发生脊柱侧弯的风险是特发性脊柱侧弯的10倍以上。34%的患者发现有脊柱畸形,包括脊柱侧弯和/或后凸。脊柱侧弯患者的矢状面排列倾向于后凸。

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