Imbelloni Luiz Eduardo, Vieira Eneida Maria, Gouveia Marildo A, Netinho João Gomes, Spirandelli Luciano Dechichi, Cordeiro José Antonio
Institute for Regional Anesthesia, Hospital de Base da FAMERP, São José do Rio Preto, SP, Brazil.
Dis Colon Rectum. 2007 Oct;50(10):1656-61. doi: 10.1007/s10350-007-0216-7.
Postoperative pain after hemorrhoidectomy is very intense, and the pain at the first postoperative defecation is very intense. Based on our pilot initial results that reflected reduced postoperative pain, we conducted a prospective, randomized, double-blind study to investigate whether the analgesia produced by bilateral pudendal nerve block using a nerve-stimulator could provide better postoperative pain relief compared with the routine technique in use in the Department of Anesthesia.
After Ethical Committee approval and informed consent, 100 patients scheduled for hemorrhoidectomy were randomized into control (C) and study (P) groups with 50 patients each. Bilateral pudendal nerve block with 0.25 percent bupivacaine was performed with nerve-stimulator. Evaluated parameters were pain severity, duration of analgesia, demand analgesia, and possible technique-related complications. Data were evaluated 6, 12, 18, and 24 hours after surgery completion. The first defecation and patient satisfaction were recorded.
Successful pudendal nerves stimulation was achieved in all patients in the study group. The pudendal nerve block group was found to have better postoperative pain relief, reduced need for analgesics, and patient satisfaction. Mean analgesic duration was 23.8 +/- 4.8 hours vs. 3.6 +/- 1 hours. All patients in the pudendal nerve block had spontaneous micturition vs. 48 patients in the control group. The pudendal analgesia was considered excellent by 44 patients and satisfactory by 6 male patients. The six male patients complained because of penile anesthesia. No anesthetic-related local or systemic complications were observed.
In this controlled study, bilateral pudendal nerve block oriented by nerve stimulator provided excellent analgesia with low need for opioids, without local or systemic complications, and without urinary retention.
痔切除术后的疼痛非常剧烈,术后首次排便时的疼痛尤为明显。基于我们初步试验结果显示术后疼痛有所减轻,我们开展了一项前瞻性、随机、双盲研究,以探究使用神经刺激器进行双侧阴部神经阻滞所产生的镇痛效果与麻醉科常规技术相比,是否能提供更好的术后疼痛缓解。
经伦理委员会批准并获得知情同意后,将100例计划行痔切除术的患者随机分为对照组(C组)和研究组(P组),每组50例。使用神经刺激器对双侧阴部神经进行0.25%布比卡因阻滞。评估参数包括疼痛严重程度、镇痛持续时间、按需镇痛情况以及可能的技术相关并发症。在手术结束后6、12、18和24小时对数据进行评估。记录首次排便情况和患者满意度。
研究组所有患者均成功实现阴部神经刺激。发现阴部神经阻滞组术后疼痛缓解更好,镇痛药物需求减少,患者满意度更高。平均镇痛持续时间为23.8±4.8小时,而对照组为3.6±1小时。阴部神经阻滞组所有患者均能自主排尿,而对照组有48例患者出现排尿困难。44例患者认为阴部神经阻滞镇痛效果极佳,6例男性患者认为满意。6例男性患者因阴茎麻木而抱怨。未观察到与麻醉相关的局部或全身并发症。
在这项对照研究中,以神经刺激器为导向的双侧阴部神经阻滞提供了极佳的镇痛效果,对阿片类药物需求低,无局部或全身并发症,也无尿潴留。