Fichter Manfred M, Quadflieg Norbert
Department of Psychiatry, University of Munich (LMU), Munich, Germany.
Int J Eat Disord. 2007 Nov;40 Suppl:S61-6. doi: 10.1002/eat.20443.
Data on the stability of eating disorder (ED) diagnoses (DSM-IV) over 12 years are presented for a large sample (N = 311) of female eating disordered patients with anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED).
Assessments were made at the beginning of therapy and 2-, 6-, and 12-year follow-ups. Diagnoses were derived from the Structured Inventory for Anorexic and Bulimic Eating Disorders. Possible diagnostic outcome categories were AN, BN, BED, NOS, no ED, and deceased.
At all follow-ups, more patients changed from AN or BED to BN than vice versa. No diagnostic crossover from AN to BED or vice versa occurred. BED showed the greatest variability and AN had the greatest stability over time. While the long-term outcome of BN and BED is similar, AN had a considerably worse long-term outcome than either BN or BED.
Of the ED diagnoses, AN was most stable and BED most variable. The considerable diagnostic flux between BN and BED and similarities in course and outcome of BN and BED point to common biological and psychological maintaining processes. AN and BED are nosologically quite distant.
呈现针对大量女性饮食失调患者样本(N = 311)的饮食失调(ED)诊断(DSM - IV)在12年期间的稳定性数据,这些患者患有神经性厌食症(AN)、神经性贪食症(BN)和暴饮暴食症(BED)。
在治疗开始时以及2年、6年和12年随访时进行评估。诊断源自厌食和贪食饮食失调结构化量表。可能的诊断结果类别为AN、BN、BED、未特定的(NOS)、无饮食失调以及死亡。
在所有随访中,从AN或BED转变为BN的患者比从BN转变为AN或BED的患者更多。未发生从AN到BED或反之的诊断交叉。随着时间推移,BED表现出最大的变异性,而AN具有最大的稳定性。虽然BN和BED的长期结果相似,但AN的长期结果比BN或BED都要差得多。
在饮食失调诊断中,AN最稳定,BED最具变异性。BN和BED之间存在相当大的诊断变化,且BN和BED在病程和结果上的相似性表明存在共同的生物和心理维持过程。AN和BED在分类学上相距甚远。