Xiong C F, Fang Y, Zhou L P, Zhang X F, Ye J J, Li G M, Liu X, Wang X J, Yang C F
Institute of Tuberculosis Control and Prevention, Hubei Provincial Centre for Disease Control and Prevention, Wuhan, People's Republic of China.
Int J Tuberc Lung Dis. 2007 Sep;11(9):1004-7.
To explore new approaches to increase the detection of tuberculosis cases (TB).
Thirty counties participated in the study. Patients with TB symptoms were surveyed and referred by trained village doctors to county dispensaries, designated township health centres or general hospitals for free sputum examination. TB patients and suspects notified by general hospitals were traced by TB staff if they defaulted during the transfer.
A total of 12,091 new smear-positive TB cases were detected. The registration rate of new smear-positives increased from 36.2 per 100,000 population before the project to 49.9/100,000 after the project, and the case detection rate under the DOTS strategy reached 86%. Of 43,464 registered TB suspects, 15,363 (35.3%) were referred by village and hospital doctors. The referral rate increased significantly (P < 0.01). Of the 15,363 referred patients, 3870 were diagnosed as new smear-positive TB cases. Among three different microscopy centres, there was a statistically significant difference in the sputum examination rates of TB suspects and in the smear-positive rates among the suspects examined. The follow-up rate was 70.9%, but the follow-up success rate was only 33.1%.
Intensive referral of patients with TB symptoms by village doctors to TB dispensaries is an effective way of increasing detection. At the same time, incentives are necessary for patients and village doctors.
探索提高结核病病例(TB)检出率的新方法。
30个县参与了该研究。有结核病症状的患者接受了调查,并由经过培训的乡村医生转诊至县级药房、指定的乡镇卫生院或综合医院进行免费痰检。如果综合医院通报的结核病患者和疑似患者在转诊过程中违约,结核病防治人员会对其进行追踪。
共检测出12091例新的涂片阳性结核病病例。新涂片阳性病例的登记率从项目实施前的每10万人口36.2例增加到项目实施后的49.9/10万,直接观察短程治疗(DOTS)策略下的病例检出率达到86%。在43464名登记的结核病疑似患者中,15363名(35.3%)由乡村医生和医院医生转诊。转诊率显著提高(P<0.01)。在15363名转诊患者中,3870名被诊断为新的涂片阳性结核病病例。在三个不同的显微镜检查中心,结核病疑似患者的痰检率以及受检疑似患者中的涂片阳性率存在统计学显著差异。随访率为70.9%,但随访成功率仅为33.1%。
乡村医生将有结核病症状的患者集中转诊至结核病防治所是提高检出率的有效方法。同时,有必要对患者和乡村医生给予激励。