Shah Ajit
Department of Ageing, Ethnicity and Mental Health, University of Central Lancashire, Preston, UK.
Int J Geriatr Psychiatry. 2008 Mar;23(3):308-13. doi: 10.1002/gps.1880.
An independent relationship between smoking cigarettes and completed suicides has been reported in several cohort and case-control studies of younger subjects, but this relationship has rarely been examined in the elderly.
The relationship between the prevalence of smoking in males and females and suicide rates in males and females in the age-bands 65-74 years and 75 + years was examined using national-level aggregate data from the World Health Organisation and the United Nations Development Programme websites. In addition to univariate analysis, multivariate analysis were conducted to ascertain an independent relationship between the prevalence of smoking and elderly suicide rates.
The main findings were: (i) on univariate analysis, the prevalence of smoking in males was positively correlated with suicide rates in males aged 65-74 years and males aged 75 + years, but this relationship was absent in females and (ii) on multivariate analysis there was no independent relationship between the prevalence of smoking in males and suicide rates in males in both the elderly age-bands.
There is a case for examination of the relationship between smoking and elderly suicides in individual-level cohort or case-control studies because of the potential methodological difficulties in cross-national studies using national- level aggregate data, paucity of cohort or case-control studies at an individual-level in the elderly, and the observation of an independent relationship between smoking and completed suicides in individual-level cohort and case-control studies in younger age groups.
在几项针对年轻受试者的队列研究和病例对照研究中,已报告吸烟与自杀死亡之间存在独立关联,但这种关系在老年人中很少被研究。
利用世界卫生组织和联合国开发计划署网站的国家级汇总数据,研究了65 - 74岁和75岁及以上年龄组男性和女性吸烟率与男性和女性自杀率之间的关系。除单变量分析外,还进行了多变量分析,以确定吸烟率与老年人自杀率之间的独立关系。
主要发现为:(i)单变量分析显示,65 - 74岁男性和75岁及以上男性的吸烟率与自杀率呈正相关,但女性不存在这种关系;(ii)多变量分析表明,在两个老年年龄组中,男性吸烟率与男性自杀率之间不存在独立关系。
鉴于使用国家级汇总数据进行跨国研究可能存在方法学困难、老年人个体层面的队列或病例对照研究较少,以及在年轻年龄组的个体层面队列和病例对照研究中观察到吸烟与自杀死亡之间存在独立关系,有必要在个体层面的队列或病例对照研究中考察吸烟与老年人自杀之间的关系。