长崎县神古医院胃癌大规模内镜检查结果。
Results of mass endoscopic examination for gastric cancer in Kamigoto Hospital, Nagasaki Prefecture.
作者信息
Matsumoto Satohiro, Yamasaki Kazumi, Tsuji Kenichiro, Shirahama Satoshi
机构信息
Department of Internal Medicine, Kamigoto Hospital, 1549-11 Aokata-gou, Shinkamigoto-cho, Minamimatsuura-gun, Nagasaki 857-4404, Japan.
出版信息
World J Gastroenterol. 2007 Aug 28;13(32):4316-20. doi: 10.3748/wjg.v13.i32.4316.
AIM
To examine how the introduction of endoscopy to gastric cancer screening affected survival prognosis in a regional population.
METHODS
The subjects comprised 4261 residents of Kamigoto, Nagasaki Prefecture, who underwent gastric X-ray examination for gastric cancer screening from 1991 to 1995, and all 7178 residents who underwent endoscopic examination for the same purpose from 1996 to 2003. The analysis evaluated trends in age-adjusted gastric cancer mortality rates and standard mortality ratios (SMRs) among the Kamigoto residents.
RESULTS
According to demographic statistics, the 1995 and 2000 age-adjusted gastric cancer mortality rates in Nagasaki Prefecture (per 100000 population) were 42.6 and 37.3 for males and 18.6 and 16.0 for females, while the corresponding rates in Kamigoto before and after the introduction of endoscopic screening were respectively 51.9 and 28.0, and 26.6 and 6.9. The data obtained in this study were divided into those for two periods, 1990-1996 and 1997-2006, and SMRs were calculated separately for males and females. For the first period, the SMR was 1.04 (95% CI 0.50-1.58) for males and 1.54 (95% CI 0.71-2.38) for females, while for the second period the SMR was 0.71 (95% CI 0.33-1.10) for males and 0.62 (95% CI 0.19-1.05) for females.
CONCLUSION
Following the introduction of endoscopic examination, gastric cancer death rates decreased in Kamigoto.
目的
研究在区域人群中引入内镜检查进行胃癌筛查对生存预后的影响。
方法
研究对象包括1991年至1995年期间因胃癌筛查接受胃X线检查的长崎县神户市4261名居民，以及1996年至2003年期间因相同目的接受内镜检查的所有7178名居民。分析评估了神户市居民年龄调整后的胃癌死亡率和标准化死亡率（SMR）趋势。
结果
根据人口统计学统计，长崎县1995年和2000年男性年龄调整后的胃癌死亡率（每10万人）分别为42.6和37.3，女性分别为18.6和16.0，而在内镜筛查引入前后神户市的相应死亡率分别为51.9和28.0，以及26.6和6.9。本研究获得的数据分为1990 - 1996年和1997 - 2006年两个时期，并分别计算了男性和女性的SMR。第一个时期，男性的SMR为1.04（95%CI 0.50 - 1.58），女性为1.54（95%CI 0.71 - 2.38），而第二个时期，男性的SMR为0.71（95%CI 0.33 - 1.10），女性为0.62（95%CI 0.19 - 1.05）。
结论
引入内镜检查后，神户市的胃癌死亡率下降。
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