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一种解释多囊卵巢综合征(PCOS)高发病率的进化方法。

An evolutionary approach to explain the high frequency of the polycystic ovary syndrome (PCOS).

作者信息

Eggers Sabine, Hashimoto Dalva Megumi, Kirchengast Sylvia

机构信息

Laboratório de Antropologia Biológica, Depto de Genética e Biologia Evolutiva, Instituto de Biociências, University of São Paulo, Brazil.

出版信息

Anthropol Anz. 2007 Jun;65(2):169-79.

Abstract

Infertility and sterility are worldwide phenomena with a long history. At a first glance a condition causing sterility seems to be paradox in an evolutionary sense because it contradicts the biogenetical imperative. In the present paper an evolutionary explanation for the high prevalence rate of PCOS, the most common endocrine disorder causing female infertility, is presented. The symptomatology of PCOS is described and the high prevalence rates of PCOS are explained by means of Darwinian medicine, kin selection and allomothering.

摘要

不孕不育是一种历史悠久的全球性现象。乍一看,导致不育的状况在进化意义上似乎自相矛盾,因为它与生物遗传的必要性相矛盾。在本文中,我们提出了一种对多囊卵巢综合征(PCOS)高患病率的进化解释,PCOS是导致女性不孕的最常见内分泌疾病。本文描述了PCOS的症状,并通过达尔文医学、亲缘选择和异亲抚育来解释PCOS的高患病率。

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