多囊卵巢综合征：一种古老的疾病？
Polycystic ovary syndrome: an ancient disorder?
机构信息
Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
出版信息
Fertil Steril. 2011 Apr;95(5):1544-8. doi: 10.1016/j.fertnstert.2010.09.032. Epub 2010 Oct 27.
Abstract
Polycystic ovary syndrome (PCOS) appears to be an ancient disorder, which has persisted in human evolution despite reduced fecundity because of the benefits to affected women such as greater sturdiness and improved energy utilization, a rearing advantage for their children and kin, and a reduction in the risk of perinatal mortality. This raises the possibility that gene variants that are eventually found to be associated with PCOS will be similar across ethnic groups and races.
摘要
多囊卵巢综合征（PCOS）似乎是一种古老的疾病，尽管其生育能力下降，但由于对受影响女性的益处，如更强壮的身体和改善的能量利用，对其子女和亲属的养育优势，以及降低围产期死亡率的风险，这种疾病在人类进化中得以持续存在。这就提出了一个可能性，即最终与 PCOS 相关的基因变异在不同种族和民族中可能是相似的。
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本文引用的文献
1
[Not Available].[无可用内容]。
Signs (Chic). 1975;1:567-84. doi: 10.1086/493243.
2
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Gynecol Obstet Invest. 2010;69(4):274-280. doi: 10.1159/000277640. Epub 2010 Jan 25.
3
Computed tomographic assessment of atherosclerosis in ancient Egyptian mummies.古埃及木乃伊动脉粥样硬化的计算机断层扫描评估
JAMA. 2009 Nov 18;302(19):2091-4. doi: 10.1001/jama.2009.1641.
4
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7
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8
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9
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10
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