赛庚啶对左旋多巴诱导的血浆促肾上腺皮质激素-皮质醇和促肾上腺皮质激素-生长激素分泌的自发性昼夜变化的影响。
Effect of cyproheptadine on the spontaneous diurnal variations of plasma ACTH-cortisol and ACTH-GH secretion induced by l-dopa.
作者信息
Delitala G, Masala A, Alagna S, Devilla L
出版信息
Biomedicine. 1975 Dec 20;23(10):406-9.
PMID:177112
Abstract
Cyproheptadine administration resulted in marked reduction and complete inhibition of the GH and ACTH-cortisol responses to L-dopa in a group of healthy subjects. If this drug acts by antagonizing serotonin, as assumed, this study suggests that serotonin is also involved in L-dopa induced GH and ACTH release.
摘要
在一组健康受试者中，服用赛庚啶导致对左旋多巴的生长激素（GH）和促肾上腺皮质激素 - 皮质醇反应显著降低并完全受到抑制。如果这种药物如所设想的那样通过拮抗血清素起作用，那么这项研究表明血清素也参与左旋多巴诱导的生长激素和促肾上腺皮质激素释放。
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