Zhang Huanzhu, Song Weimin
School of Public Health, Fudan University, Shanghai 200032, China.
Wei Sheng Yan Jiu. 2007 May;36(3):269-72.
Study adverse effects of volatile organic compounds volatile organic compounds (VOCs) on brain amino acid neurotransmitter in mice.
Four groups of mouse were respectively exposed to 0, low, middle and high concentration of VOCs for two hours every day for 30 days. The content of brain amino acid neurotransmitter was determined.
The result showed that the content of Glu and ASP in brain of VOCs -exposed mouse decreased and GABA and Gly increased compared with that of control.
The memory impair in mice induced by exposing VOCs may relate to the chang of content of amino acid neurotransmitter.
研究挥发性有机化合物（VOCs）对小鼠脑内氨基酸神经递质的不良反应。
将四组小鼠分别每天暴露于0、低、中、高浓度的VOCs中，持续2小时，共30天。测定脑内氨基酸神经递质的含量。
结果显示，与对照组相比，暴露于VOCs的小鼠脑内Glu和ASP含量降低，GABA和Gly含量升高。
暴露于VOCs诱导的小鼠记忆损伤可能与氨基酸神经递质含量的变化有关。
