Zervoudis S, Iatrakis G, Navrozoglou I, Veduta A, Vladareanu R
Technological Educational Institution of Athens, Greece.
Eur J Gynaecol Oncol. 2007;28(4):307-9.
Pathologic nipple discharge presents a diagnostic dilemma as no one diagnostic test has proven clearly superior to any other in the differentiation of benign versus malignant conditions. This is a clinical study of 80 patients with unilateral suspicious nipple discharge whose complete investigation included histological evaluation. A transnipple approach was used to identify, get to and excise the breast tissue suspicious of having caused the pathological discharge, with a pyramide-shaped tissue dissection (pyramidectomy). Specimens satisfactory for histological evaluation were obtained in all cases. Breast cancer was detected in six cases, papillomatosis in four, papillomas in 30, fibrocystic changes in five, ductal ectasia in 31 and non specific findings in four cases. There were no intraoperative complications and functional and healing-esthetic recovery was very good in all cases. It is concluded that transnipple pyramidectomy is a useful technique for a reliable diagnosis of pathologic nipple discharge.
病理性乳头溢液带来了诊断难题,因为在鉴别良性与恶性疾病方面,尚无一种诊断测试被明确证明比其他测试更具优势。这是一项针对80例单侧可疑乳头溢液患者的临床研究,其完整检查包括组织学评估。采用经乳头入路来识别、到达并切除怀疑导致病理性溢液的乳腺组织,进行锥形组织切除(锥形切除术)。所有病例均获得了适合组织学评估的标本。检测出乳腺癌6例,乳头状瘤病4例,乳头状瘤30例,纤维囊性变5例,导管扩张31例,4例为非特异性发现。术中无并发症,所有病例的功能及愈合美观恢复情况均非常好。结论是经乳头锥形切除术是一种用于可靠诊断病理性乳头溢液的有用技术。