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[新定义对哥伦比亚布卡拉曼加成年人群代谢综合征患病率的影响]

[Impact of the new definitions in the prevalence of the metabolic syndrome in an adult population at Bucaramanga, Colombia].

作者信息

Pinzón Juan Bernardo, Serrano Norma Cecilia, Díaz Luis Alfonso, Mantilla Gerardo, Velasco Harvey Mauricio, Martínez Luz Ximena, Millán Paula Andrea, Acevedo Sandra Milena, Moreno Daniel

机构信息

Centro de Investigaciones Biomédicas, Facultad de Medicina, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia.

出版信息

Biomedica. 2007 Jun;27(2):172-9. Epub 2007 Aug 21.

Abstract

INTRODUCTION

The prevalence of metabolic syndrome depends on the criteria used for its classification. Three criteria in common use are those from International Diabetes Federation (IDF), the Adult Treatment Panel (ATP-III) or its update (ATP-IIIa).

OBJECTIVE

The prevalence statistic for generated metabolic syndrome was compared on the basis of each of the three criteria in an adult population.

MATERIALS AND METHODS

The sample consisted of 155 teachers and employees in the school of medicine. The average age was 40.9; 54.2% were men. The three criteria were applied and the prevalences were compared with the Wilcoxon test and Cohen's kappa.

RESULTS

Metabolic syndrome prevalence generated by each criterion was as follows: ATP-III was 12.3% (95%CI 7.5-18.5), ATP-IIIa was 34.8% (95%CI 27.4-42.9) and IDF 32.9% (95%CI 25.6--40.9). The prevalence indicated by ATP-III was lower than the ATP-IIIa or IDF prevalences (p < 0,001); however those of ATPIII-a and IDF were similar (p=0,083). Poor agreement was seen between ATP-III and ATP-IIIa (k=0.414, IC95% 0.409-0.420), and between ATP-III and IDF (k=0.374, IC95% 0.368-0.379); however, very good agreement was obtained between ATP-IIIa and IDF (k=0.957, IC95% 0.950-0.963).

CONCLUSION

The new definitions for metabolic syndrome, ATP-IIIa and IDF, increase the prevalence statistic by three times. This occurred despite the inclusion in IDF of an obesity factor in the criteria set.

摘要

引言

代谢综合征的患病率取决于用于其分类的标准。常用的三个标准分别来自国际糖尿病联盟(IDF)、成人治疗小组(ATP-III)或其更新版本(ATP-IIIa)。

目的

在成年人群中,基于这三个标准中的每一个,比较生成的代谢综合征的患病率统计数据。

材料与方法

样本包括医学院的155名教师和员工。平均年龄为40.9岁;男性占54.2%。应用这三个标准,并通过威尔科克森检验和科恩卡方检验比较患病率。

结果

各标准生成的代谢综合征患病率如下:ATP-III为12.3%(95%CI 7.5-18.5),ATP-IIIa为34.8%(95%CI 27.4-42.9),IDF为32.9%(95%CI 25.6-40.9)。ATP-III显示的患病率低于ATP-IIIa或IDF的患病率(p < 0.001);然而,ATPIII-a和IDF的患病率相似(p = 0.083)。ATP-III与ATP-IIIa之间的一致性较差(k = 0.414,IC95% 0.409-0.420),ATP-III与IDF之间的一致性也较差(k = 0.374,IC95% 0.368-0.379);然而,ATP-IIIa与IDF之间的一致性非常好(k = 0.957,IC95% 0.950-0.963)。

结论

代谢综合征的新定义ATP-IIIa和IDF使患病率统计数据增加了两倍。尽管IDF的标准集中纳入了肥胖因素,但仍出现了这种情况。

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