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[交感神经元中含微丝和微管的核内包涵体出现的机制。二丁酰腺苷3'-5'单磷酸和茶碱的影响]

[Mechanism of the appearance of nuclear inclusions with microfilaments and microtubules in sympathetic neurons. Influence of dibutyryl-adenosine 3'-5' monophosphate and theophylline].

作者信息

Leonetti J, Seite R, Luciani-Vuillet J, Vio M

出版信息

Bull Assoc Anat (Nancy). 1975 Sep;59(166):651-6.

PMID:177138
Abstract

As we have shown previously the nucleus of sympathetic neurons contains microtubules and microfilaments giving rise to highly organized inclusions. Present in vivo experiments on cat stellate ganglia have shown that dibutyryl cyclic AMP and theophyllin induce an increase of their frequency (up to 8.5 fold). These and earlier observations lead us to conclude that cyclic AMP mediates the process of nuclear microtubules and microfilaments assembly from preformed protein subunits.

摘要

正如我们之前所表明的，交感神经元的细胞核含有微管和微丝，会形成高度有序的内含物。对猫星状神经节进行的体内实验表明，二丁酰环磷腺苷和茶碱会使其频率增加（高达8.5倍）。这些以及早期的观察结果使我们得出结论，环磷腺苷介导了由预先形成的蛋白质亚基组装核微管和微丝的过程。

相似文献

1
[Mechanism of the appearance of nuclear inclusions with microfilaments and microtubules in sympathetic neurons. Influence of dibutyryl-adenosine 3'-5' monophosphate and theophylline].[交感神经元中含微丝和微管的核内包涵体出现的机制。二丁酰腺苷3'-5'单磷酸和茶碱的影响]
Bull Assoc Anat (Nancy). 1975 Sep;59(166):651-6.
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[Influence of dibutyryl cyclic AMP and theophylline on the frequency of nuclear microtubules and microfilaments of sympathetic neurons].
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