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基于扩散张量磁共振成像的三维白质纤维束成像

[Three-dimensional white matter tractography based on diffusion-tensor magnetic resonance imaging].

作者信息

Li Yi-Zhuo, Huang Zi-Lin, Wei Yi-Fei, Xie Chuan-Miao, He Hao-Qiang, Wei Da-Nian, Chen Lin, Wu Pei-Hong

机构信息

Tumor Hospital, Sun Yat-sen University, Guangzhou, China.

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2007 Aug;27(8):1244-7.

PMID:17715038
Abstract

OBJECTIVE

To assess the value of white matter fiber tractography based on magnetic resonance diffusion-tensor imaging (MR-DTI), a new noninvasive technique that helps estimate the structural connectivity of the brain, in understanding the anatomy of the white matter fiber tract.

METHODS

Six consecutive volunteers received MR-DTI examination using a GE 1.5T Sign CV/I whole-body MR system and version 2.0 Functool software for image processing. The protocol included T1WI for localization and single-shot echo-planner diffusion tensor imaging of the entire brain in axial, sagittal, and /or coronal sections.

RESULTS

White matter fiber tracts imaged by MR-DTI were consistent with known white matter fiber anatomy. The major fiber tracts were well observed in all the cases. The tracts visualized included the corpus callosum, anterior commissure, uncinate fasciculus superior and inferior longitudinal fascicules, inferior occipito-frontal fasciculus, internal capsule and corona radiate.

CONCLUSION

A set of detailed white matter fiber anatomy maps of the normal brain is obtained by means of single-shot echo-planner diffusion tensor imaging at high resolution. This technique allows rapid visualization of the white matter tracts in vivo, and provides a new reliable means for studying fiber connectivity in the brain.

摘要

目的

评估基于磁共振扩散张量成像(MR-DTI)的白质纤维束成像技术的价值,这是一种有助于估计脑结构连通性的新型无创技术,用于了解白质纤维束的解剖结构。

方法

连续6名志愿者使用GE 1.5T Sign CV/I全身MR系统及2.0版Functool软件进行MR-DTI检查以进行图像处理。检查方案包括用于定位的T1WI以及在轴位、矢状位和/或冠状位对全脑进行的单次激发回波平面扩散张量成像。

结果

MR-DTI成像的白质纤维束与已知的白质纤维解剖结构一致。所有病例中主要纤维束均清晰可见。显示的纤维束包括胼胝体、前连合、钩束、上纵束和下纵束、枕额下束、内囊和放射冠。

结论

通过高分辨率的单次激发回波平面扩散张量成像获得了一组正常脑白质纤维解剖结构的详细图谱。该技术可在体内快速显示白质纤维束,为研究脑内纤维连通性提供了一种新的可靠方法。

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