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软骨环对气管和主支气管中气流及颗粒沉积的影响。

Effects of cartilage rings on airflow and particle deposition in the trachea and main bronchi.

作者信息

Russo J, Robinson R, Oldham Michael J

机构信息

Department of Mechanical Engineering, Rochester Institute of Technology, Rochester, NY, United States.

出版信息

Med Eng Phys. 2008 Jun;30(5):581-9. doi: 10.1016/j.medengphy.2007.06.010. Epub 2007 Aug 23.

Abstract

In most computational fluid dynamic (CFD) analysis of the human lung, it has been assumed that the trachea and branches of the lung have smooth walls. In order to determine if this is a valid assumption, the effects of cartilage rings on airflow and particle deposition in the lungs was determined through conducting simulations with two CFD packages, Fluent and CFX. A smooth walled model and a ringed model of the trachea and main bronchi were created based on idealized models with realistic characteristics. Turbulent velocity profiles were implemented at the inlet of the trachea to account for the laryngeal jet at 15, 30 and 60 lpm's, while random and uniform distributions of particles were injected into the airways. Deposition of particles through sedimentation and impaction were recorded and compared for each model at each flow rate. The results of this work show that the effects of cartilage rings increase with the size of particles and flow rate.

摘要

在大多数对人类肺部的计算流体动力学(CFD)分析中,人们一直假定气管和肺的分支具有光滑的管壁。为了确定这是否是一个有效的假设,通过使用两个CFD软件包Fluent和CFX进行模拟,确定了软骨环对肺部气流和颗粒沉积的影响。基于具有实际特征的理想化模型,创建了气管和主支气管的光滑壁模型和带环模型。在气管入口处设置了湍流速度剖面,以考虑15、30和60升/分钟时的喉喷流,同时将颗粒的随机和均匀分布注入气道。记录并比较了每个模型在每个流速下通过沉降和撞击造成的颗粒沉积情况。这项工作的结果表明,软骨环的影响随着颗粒大小和流速的增加而增大。

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