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Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand.

作者信息

U'ren Jana M, Hornstra Heidie, Pearson Talima, Schupp James M, Leadem Benjamin, Georgia Shalamar, Sermswan Rasana W, Keim Paul

机构信息

Northern Arizona University, Department of Biological Sciences, Box 5640, Flagstaff, AZ 86011-5640, USA.

出版信息

Appl Environ Microbiol. 2007 Oct;73(20):6678-81. doi: 10.1128/AEM.00986-07. Epub 2007 Aug 24.

Abstract

Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation.

摘要

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