Zaninotto Giovanni, Portale Giuseppe, Costantini Mario, Fiamingo Pietro, Rampado Sabrina, Guirroli Emanuela, Nicoletti Loredana, Ancona Ermanno
Department of Gastroenterological and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Via Giustiniani 2, 35128 Padova, Italy.
World J Surg. 2007 Nov;31(11):2177-83. doi: 10.1007/s00268-007-9212-2. Epub 2007 Aug 29.
Symptomatic results of laparoscopic repair of large type III hiatal hernias, with/without prosthetic mesh, are often excellent; however, a high recurrence rate is detected when objective radiological/endoscopic follow-up is performed. The use of mesh may reduce the incidence of postoperative hernia recurrence or wrap migration in the chest.
We retrospectively studied 54 patients (10 men, 44 women; median: age 64.5 years) with a diagnosis of large type III hiatal hernia (>1/3 stomach in the chest on x-ray) who underwent laparoscopic repair at our department from January 1992 to June 2005. Complications, recurrences, and symptomatic and objective (radiological/endoscopic) long-term outcome were evaluated.
Nineteen patients had laparoscopic Nissen/Toupet fundoplication with simple suture; in 35 patients a double mesh was added. The median radiological/endoscopic follow-up was 64 months (interquartile range (IQR): 6-104) for the non-mesh group and 33 (IQR:12-61) for the mesh group (p = 0.26). Recurrences occurred in 11/54 (20%) patients: 8/19 (42.1%) without mesh and 3/35 (8.6%) with mesh (p = 0.01). The 3 recurrences in the mesh group all occurred < or =12 months postoperatively; 4/8 recurrences in the non-mesh group occurred > or =5 years after operation. On multivariate logistic regression analysis, only mesh absence significantly predicted hernia recurrence or wrap migration.
Laparoscopic repair of large type III hiatal hernias is safe and effective. Short-term symptomatic results are excellent, but mid-term objective radiological/endoscopic evaluation reveals a high recurrence rate. Possible reasons for failure of a laparoscopic hiatal repair are tension or poor muscle tissue characteristics in the hiatus. The use of a mesh, either by reducing tension or reinforcing muscle at the hiatus, might be associated with a lower recurrence rate. Longer-term follow-up will be needed before definitive conclusions can be drawn, however.
大型III型食管裂孔疝行腹腔镜修补术,无论有无使用人工补片,其症状改善结果通常都很好;然而,在进行客观的影像学/内镜随访时,发现复发率很高。使用补片可能会降低术后疝复发或补片在胸腔内移位的发生率。
我们回顾性研究了1992年1月至2005年6月在我科接受腹腔镜修补术的54例诊断为大型III型食管裂孔疝(X线显示胸腔内胃>1/3)的患者(10例男性,44例女性;中位年龄:64.5岁)。评估了并发症、复发情况以及症状性和客观性(影像学/内镜)长期结局。
19例患者行腹腔镜Nissen/Toupet胃底折叠术并单纯缝合;35例患者加用了双层补片。非补片组的中位影像学/内镜随访时间为64个月(四分位间距(IQR):6 - 104),补片组为33个月(IQR:12 - 61)(p = 0.26)。54例患者中有11例(20%)复发:未使用补片的19例中有8例(42.1%)复发,使用补片的35例中有3例(8.6%)复发(p = 0.01)。补片组的3例复发均发生在术后≤12个月;未使用补片组的8例复发中有4例发生在术后≥5年。多因素逻辑回归分析显示,仅未使用补片是疝复发或补片移位的显著预测因素。
大型III型食管裂孔疝的腹腔镜修补术安全有效。短期症状改善结果良好,但中期客观的影像学/内镜评估显示复发率很高。腹腔镜食管裂孔修补术失败的可能原因是裂孔处张力过大或肌肉组织特性不佳。使用补片,无论是通过减轻张力还是加强裂孔处的肌肉,都可能与较低的复发率相关。然而,在得出明确结论之前,还需要更长时间的随访。