Bean G J, Marchese V, Martin B A
Epidemiology and Biostatistics Research Section, Clarke Institute of Psychiatry, Toronto, Ontario.
Can J Psychiatry. 1991 Nov;36(9):637-44. doi: 10.1177/070674379103600903.
The relationship between electric stimulus energy and clinical response was examined in depressed patients receiving electroconvulsive therapy (ECT) under routine clinical conditions with a protocol which dichotomized the stimulus energy by patient age. There was no significant difference in the number of treatments and cumulative seizure duration between groups. The results support the observation that the stimulus energy may contribute to the therapeutic effect of ECT. Reduction of that energy in order to minimize side-effects may compromise the therapeutic effectiveness. The implications for dosage strategies in routine clinical practice are discussed.
在常规临床条件下，采用按患者年龄将刺激能量二分法的方案，对接受电休克治疗（ECT）的抑郁症患者的电刺激能量与临床反应之间的关系进行了研究。两组之间的治疗次数和累积癫痫发作持续时间没有显著差异。结果支持了刺激能量可能有助于ECT治疗效果的观察。为尽量减少副作用而降低该能量可能会损害治疗效果。文中讨论了其对常规临床实践中剂量策略的影响。
