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猪苓多糖对肝损伤小鼠腹腔巨噬细胞功能的影响

[Effect of Polyporus umbellatus polysaccharide on function of macrophages in the peritoneal cavities of mice with liver lesions].

作者信息

Zhang Y H, Liu Y L, Yan S C

机构信息

Institute of Chinese Materia Medica, China Academy of TCM, Beijing.

出版信息

Zhong Xi Yi Jie He Za Zhi. 1991 Apr;11(4):225-6, 198.

PMID:1773459
Abstract

The cells in peritoneal cavities of mice were taken out and cultured in vitro. The amount to release H2O2 of the macrophages was assayed by fluorimetry. Polyporus umbellatus polysaccharide (PUP) could not only increase the number of macrophages and the amount of H2O2 release in the peritoneal cavities of normal mice, but also raise the lowered number of macrophages and the ability to release H2O2 in the peritoneal cavities of the mice with liver lesions caused by CCl4 significantly. So PUP could improve the cellular immunity of normal mice and the mice with liver lesions.

摘要

取出小鼠腹腔内的细胞并进行体外培养。采用荧光分析法检测巨噬细胞释放过氧化氢(H₂O₂)的量。猪苓多糖(PUP)不仅能增加正常小鼠腹腔内巨噬细胞数量及H₂O₂释放量,还能显著提高四氯化碳所致肝损伤小鼠腹腔内降低的巨噬细胞数量及H₂O₂释放能力。因此,PUP可改善正常小鼠及肝损伤小鼠的细胞免疫功能。

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