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[使用手术刀、电灼术和二氧化碳激光束进行实验性手术后口腔伤口愈合的比较研究]

[Comparative study on wound healing in the oral cavity following experimental surgery using a scalpel, electrocauterization and CO2 laser beam].

作者信息

Gáspár L, Tóth J

机构信息

Semmelweis Orvostudományi Egyetem, Szájsebészeti és Fogászati Klinika, Budapest.

出版信息

Fogorv Sz. 1991 Nov;84(11):339-43.

PMID:1773835
Abstract

In the mouth cavity of white rats lesion was created by means of surgical scalpel and electrokauter the course of the wound healing was observed on basis operations of various types (coagulation, vaporization, excision) as well as scalpel and electrokauter the course of the wound healing was observed on basis of histological examination of biopsies taken on the second, fifth, tenth, twentieth and fortieth day. It was verified that the wound healing is excellent after all three types of laser surgical intervention and is significantly more favourable than in case of electrokauter. The course of healing is finished during 3 weeks after coagulation and vaporaziation, and during 4 weeks after excision. The new epithelium layer became thinner than the original while the submucosa became twice as thick. The laser treated surfaces are protected by coagulation proteins, the wound edges are sharp, the amount of the cicatrice tissue formed after the wound healing is less than after the employment of the scalpel and the electrokauter.

摘要

在白鼠口腔内,用手术刀和电烙器制造损伤,基于不同类型的手术操作(凝固、汽化、切除)观察伤口愈合过程,同时用手术刀和电烙器,根据在第2天、第5天、第10天、第20天和第40天采集的活检组织的组织学检查观察伤口愈合过程。结果证实,三种激光手术干预后伤口愈合良好,且明显优于电烙术。凝固和汽化后3周内愈合过程完成,切除后4周内完成。新的上皮层比原来变薄,而黏膜下层增厚两倍。激光治疗的表面由凝固蛋白保护,伤口边缘锐利,伤口愈合后形成的瘢痕组织量比使用手术刀和电烙器后少。

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