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采用免疫放射分析法定量检测红细胞上的HLA抗原。

Quantitation of HLA antigens on red cells by immunoradiometric assay.

作者信息

Chablani U A, Contractor N M, Gupte S C

机构信息

Institute of Immunohaematology (ICMR), Bombay.

出版信息

Indian J Med Res. 1991 Dec;94:457-60.

PMID:1774100
Abstract

Immunoradiometric assay was employed to quantitate HLA antigens on red cells. Using this technique HLA-B7, HLA-B17 and HLA-A28 were detected on the red cells of all individuals studied irrespective of the serological status of the Bennett-Goodspeed (Bg) antigens. However, HLA antigenic sites for serologically Bg positive red cells were significantly more than that for Bg negative red cells (P less than 0.001). Bga positive red cells possessed maximum number of antigenic sites as compared to Bgb and Bgc positive red cells.

摘要

采用免疫放射分析法定量检测红细胞上的HLA抗原。运用该技术,在所研究的所有个体的红细胞上均检测到了HLA - B7、HLA - B17和HLA - A28,而不论其Bennett - Goodspeed(Bg)抗原的血清学状态如何。然而,血清学检测为Bg阳性的红细胞的HLA抗原位点显著多于Bg阴性的红细胞(P小于0.001)。与Bgb和Bgc阳性的红细胞相比,Bga阳性的红细胞具有最多数量的抗原位点。

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