Sestokas A K, Lehmkuhle S, Kratz K E
Division of Neurosurgery, Maryland Institute for E.M.S. Systems, Baltimore.
Int J Neurosci. 1991 Sep;60(1-2):59-64. doi: 10.3109/00207459109082037.
This study investigates the relationship between visual response latency and amplitude in the retina and dorsal lateral geniculate nucleus (dLGN) of the anesthetized, paralyzed cat. The discharge rate profiles of retinal ganglion and dLGN X- and Y-cells were measured on a trial by trial basis during repeated stimulation with sinusoidal grating patterns. Latencies of response onsets and peaks were regressed linearly against different measures of response amplitude to determine the extent of covariance. In general, response amplitude was a poor predictor of response latency for both retinal ganglion and geniculate cells. The results suggest that response latency, which changes systematically with stimulus spatial frequency and/or contrast, is not a trivial consequence of discharge rate at either level of the visual system.
本研究调查了麻醉、麻痹猫的视网膜和背外侧膝状核（dLGN）中视觉反应潜伏期与振幅之间的关系。在使用正弦光栅图案进行重复刺激期间，逐次测量视网膜神经节以及dLGN的X细胞和Y细胞的放电率曲线。将反应起始和峰值的潜伏期与反应振幅的不同测量值进行线性回归，以确定协方差程度。总体而言，对于视网膜神经节细胞和膝状核细胞，反应振幅都不是反应潜伏期的良好预测指标。结果表明，随刺激空间频率和/或对比度系统性变化的反应潜伏期，并非视觉系统任一水平放电率的简单结果。
