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翼状胬肉β射线照射后的复发率及并发症

Recurrence rate and complications after beta irradiation for pterygia.

作者信息

MacKenzie F D, Hirst L W, Kynaston B, Bain C

机构信息

Department of Surgery Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

出版信息

Ophthalmology. 1991 Dec;98(12):1776-80; discussion 1781. doi: 10.1016/s0161-6420(91)32051-7.

DOI:10.1016/s0161-6420(91)32051-7
PMID:1775309
Abstract

Of 1102 consecutive patients treated with beta irradiation after pterygium removal at the Queensland Radium Institute from 1973 through 1978, 503 had a follow-up ophthalmologic examination in 1989, while a further 82 had at least a 10-year follow-up from ophthalmologic records. One hundred forty-two patients were lost to follow-up because of death, lack of cooperation, and geographical inaccessibility. A further 375 patients could not be located. Of those not followed for at least 10 years, 162 had a follow-up, recorded from ophthalmologic records, of at least 3 months. After an average dose of 22 Gray, there was a recurrence rate of 12%. A further 13% showed some sign of scleromalacia, which included 4.5% of the study group who had severe thinning.

摘要

1973年至1978年期间,昆士兰镭研究所对1102例翼状胬肉切除术后接受β射线照射的连续患者进行了治疗,其中503例患者于1989年接受了眼科随访检查,另有82例患者至少有10年的眼科记录随访。142例患者因死亡、缺乏合作以及地理位置偏远而失访。另有375例患者无法找到。在那些未进行至少10年随访的患者中,162例有至少3个月的眼科记录随访。平均剂量为22戈瑞后,复发率为12%。另有13%表现出一些巩膜软化的迹象,其中包括研究组中4.5%有严重变薄的患者。

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