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胸段硬膜外麻醉的非镇痛作用

Non-analgesic effects of thoracic epidural anesthesia.

作者信息

Ulke Zerrin Sungur, Sentürk Mert

机构信息

Istanbul Faculty of Medicine, Department of Anesthesiology, Turkey.

出版信息

Agri. 2007 Apr;19(2):6-12.

PMID:17760239
Abstract

Thoracic epidural anaesthesia is selected usually to provide adequate postoperative analgesia; however with administration of local anaesthetics to epidural space selective sympatolysis ensues. The effects of this transient sympathectomy on cardivascular, respiratory and other systems deserve certainly some interest as it may influence postoperative morbidity or mortality. Thoracic epidural anaesthesia has succesfully been used in cardiac, thoracic and major abdominal surgery. It provides dynamic analgesia, rapid mobilization, blunted stress response, early extubation with reduced pulmonary complications and also rapid recovery of bowel function. In cardiac surgery where thoracic sympathetic blockade is expected to be most useful, there is no difference in morbidity and mortality. Despite the superior quality of pain control, the beneficial aspect of thoracic epidural anaesthesia is not reflected on outcome in meta-analysis. Recent papers has still demonstrated positive effects on each system. So thoracic epidural anaesthesia is increasingly used and it seems that it will be discussed more in near future.

摘要

胸段硬膜外麻醉通常用于提供充分的术后镇痛;然而,在硬膜外间隙给予局部麻醉药后会发生选择性交感神经阻滞。这种短暂性交感神经切除术对心血管、呼吸及其他系统的影响无疑值得关注,因为它可能会影响术后发病率或死亡率。胸段硬膜外麻醉已成功应用于心脏、胸部及腹部大手术。它可提供动态镇痛、快速活动能力恢复、减轻应激反应、早期拔管并减少肺部并发症,还能使肠功能快速恢复。在预计胸段交感神经阻滞最有用的心脏手术中,发病率和死亡率并无差异。尽管在疼痛控制方面质量更优,但胸段硬膜外麻醉的有益之处在荟萃分析中并未体现在结局上。近期的论文仍表明其对各个系统有积极作用。因此,胸段硬膜外麻醉的应用越来越广泛,而且似乎在不久的将来会得到更多讨论。

相似文献

1
Non-analgesic effects of thoracic epidural anesthesia.胸段硬膜外麻醉的非镇痛作用
Agri. 2007 Apr;19(2):6-12.
2
Effect of analgesic treatment on the physiological consequences of acute pain.镇痛治疗对急性疼痛生理后果的影响。
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Regional anaesthesia and perioperative outcome.区域麻醉与围手术期结局
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[Regional anaesthesia and organ protection--the role of thoracic epidural anaesthesia].[区域麻醉与器官保护——胸段硬膜外麻醉的作用]
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Myocardial protection by isoflurane vs. sevoflurane in ultra-fast-track anaesthesia for off-pump aortocoronary bypass grafting.在非体外循环主动脉冠状动脉搭桥术的超快通道麻醉中,异氟烷与七氟烷对心肌的保护作用比较
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Thoracic epidural anesthesia decreases C-reactive protein levels in patients undergoing elective coronary artery bypass graft surgery with cardiopulmonary bypass.胸段硬膜外麻醉可降低接受体外循环择期冠状动脉搭桥手术患者的C反应蛋白水平。
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Protective effects of epidural analgesia on pulmonary complications after abdominal and thoracic surgery: a meta-analysis.硬膜外镇痛对腹部和胸部手术后肺部并发症的保护作用:一项荟萃分析。
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[Patient controlled epidural analgesia: interest in thoracic surgery].[患者自控硬膜外镇痛:在胸外科手术中的应用价值]
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Cardiovascular and pulmonary effects of epidural anaesthesia.硬膜外麻醉对心血管和肺部的影响。
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The effect of thoracic epidural analgesia on short-term outcome and mortality in geriatric patients undergoing open heart surgery.胸段硬膜外镇痛对老年心脏直视手术患者短期转归和死亡率的影响。
Ulus Travma Acil Cerrahi Derg. 2022 Mar;28(3):382-389. doi: 10.14744/tjtes.2022.57995.
2
Postoperative outcome in awake, on-pump, cardiac surgery patients.清醒、非体外循环心脏手术患者的术后转归。
J Anesth. 2011 Aug;25(4):500-8. doi: 10.1007/s00540-011-1159-7. Epub 2011 May 11.
3
Breakage of a thoracic epidural catheter during its removal -A case report-.
在拔除胸腔硬膜外导管时发生断裂 - 病例报告 - 。
Korean J Anesthesiol. 2010 Jun;58(6):569-72. doi: 10.4097/kjae.2010.58.6.569. Epub 2010 Jun 23.