Sellheyer Klaus
Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Dermatol Surg. 2007 Sep;33(9):1055-65. doi: 10.1111/j.1524-4725.2007.33219.x.
Current laser hair removal modalities achieve a long-term but not persistent (irreversible) hair loss.
This review highlights the mechanisms of the current laser hair removal technology and explores possible side effects.
The literature is reviewed.
The hair shaft plays a key role in the mechanisms underlying current photoepilation procedures by acting as a vector for heat transfer. Together with inherent properties of the hair growth cycle and the anatomic specifics of the follicular stem cells located in the bulge, the crucial role of the hair shaft and its lack of complete destruction with present technology are also likely culprits for the nonpersistent nature of present laser hair removal. Future persistent photoepilation may be associated with vitiligo or vitiligolike changes. Disturbances in wound repair of previously lasered sites are less likely.
The currently available laser hair removal protocols are safe, not the least because they achieve long-term but not persistent epilation. The adverse effects of persistent laser hair removal technology possibly available in the future are potentially problematic.
目前的激光脱毛方法可实现长期但非永久性（不可逆）脱发。
本综述着重介绍当前激光脱毛技术的机制，并探讨可能的副作用。
对文献进行综述。
毛干在当前光脱毛程序的潜在机制中起着关键作用，它作为热传递的载体。结合毛发生长周期的固有特性以及位于隆突区的毛囊干细胞的解剖学特点，毛干的关键作用以及现有技术对其缺乏完全破坏，也可能是当前激光脱毛非永久性的原因。未来的永久性光脱毛可能与白癜风或白癜风样改变有关。先前接受激光治疗部位的伤口修复紊乱可能性较小。
目前可用的激光脱毛方案是安全的，尤其是因为它们能实现长期但非永久性脱毛。未来可能出现的永久性激光脱毛技术的不良反应可能存在问题。
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