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[急性白血病患者中由白吉利丝孢酵母引起的局灶性肝脾真菌病]

[Focal hepato-splenic mycosis caused by Trichosporon beigelii in a patient with acute leukemia].

作者信息

Alegre A, Algora M, Peñalver M A, Llanos M L, Pérez-Pons C, García Plaza I, Lozano M, Padilla B

机构信息

Servicio de Hematología y Hemoterapia, Hospital Severo Ochoa, Leganés, Madrid.

出版信息

Sangre (Barc). 1991 Aug;36(4):311-4.

PMID:1776110
Abstract

We report a case of infection produced by Trichosporon beigelii in a patient with acute leukaemia. In spite of treatment with amphotericin B the patient died and the necropsy studies showed only involvement of liver and spleen without disseminated infection. Focal hepatosplenic fungal infection has been recognized with increasing frequency in recent years as a serious complication in immunosuppressed patients. Usually it is produced by Candida spp and this is the first case described in the literature due to the newly recognized fungus T. beigelii.

摘要

我们报告了1例急性白血病患者感染白吉利丝孢酵母的病例。尽管使用两性霉素B进行了治疗,患者仍死亡,尸检研究显示仅肝脏和脾脏受累,无播散性感染。近年来,局灶性肝脾真菌感染作为免疫抑制患者的一种严重并发症,其被认识的频率越来越高。通常由念珠菌属引起,而这是文献中首次报道的由新发现的白吉利丝孢酵母引起的病例。

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