Doneray Hakan, Tan Huseyin, Buyukavci Mustafa, Karakelleoglu Cahit
Department of Pediatrics, Ataturk University, Faculty of Medicine, Erzurum, Turkey.
Blood Coagul Fibrinolysis. 2007 Sep;18(6):529-30. doi: 10.1097/MBC.0b013e3282010d66.
In this study, clinical and demographic features of 16 cases with late vitamin K deficiency bleeding are presented. Ages of infants were between 30 and 130 days. Their delivery histories were uneventful, and family histories for bleeding disorders were negative. All parents except one were unaware of whether their children received vitamin K at birth or not. All cases did not have any underlying illness to explain the abnormal coagulation profile. The common presenting finding was pallor (62.5%). Intracranial haemorrhage was the most common bleeding site (37.5%), and two patients (12.5%) died because of it. Late vitamin K deficiency bleeding is still an important handicap in infants. Parents and healthcare providers should be informed about the importance of vitamin K prophylaxis to prevent vitamin K deficiency in infants.
本研究报告了16例晚发性维生素K缺乏性出血患儿的临床和人口统计学特征。婴儿年龄在30至130天之间。他们的分娩史无异常,出血性疾病家族史为阴性。除1名家长外,其他所有家长均不知道其孩子出生时是否接受了维生素K。所有病例均无任何基础疾病来解释凝血异常情况。常见的临床表现为面色苍白(62.5%)。颅内出血是最常见的出血部位(37.5%),两名患儿(12.5%)因此死亡。晚发性维生素K缺乏性出血仍是婴儿的一个重要障碍。应告知家长和医护人员维生素K预防对预防婴儿维生素K缺乏的重要性。