Jörgens Silke, Kleiser Raimund, Indefrey Peter, Seitz Rüdiger J
Department of Neurology, Heinrich-Heine-University Düsseldorf, Germany.
Neuroreport. 2007 Aug 27;18(13):1339-43. doi: 10.1097/WNR.0b013e32825a67db.
We investigate differences of cerebral activation in 12 right-handed and left-handed participants, respectively, using a sentence-processing task. Functional MRI shows activation of left-frontal and inferior-parietal speech areas (BA 44, BA9, BA 40) in both groups, but a stronger bilateral activation in left-handers. Direct group comparison reveals a stronger activation in right-frontal cortex (BA 47, BA 6) and left cerebellum in left-handers. Laterality indices for the inferior-frontal cortex are less asymmetric in left-handers and are not related to the degree of handedness. Thus, our results show that sentence-processing induced enhanced activation involving a bilateral network in left-handed participants.
我们分别使用句子处理任务，对12名右利手和左利手参与者的大脑激活差异进行了研究。功能磁共振成像显示，两组参与者的左额叶和顶下言语区域（BA44、BA9、BA40）均有激活，但左利手参与者的双侧激活更强。直接的组间比较显示，左利手参与者的右额叶皮质（BA47、BA6）和左小脑激活更强。左利手参与者的额下皮质的偏侧性指数不对称性较小，且与利手程度无关。因此，我们的结果表明，句子处理在左利手参与者中诱导了涉及双侧网络的增强激活。
