Trappe H J, Klein H, Wenzlaff P, Lichtlen P R
Abteilung Kardiologie, Medizinische Hochschule Hannover.
Z Kardiol. 1991 Dec;80(12):720-6.
Treatment of incessant ventricular tachycardia (VT) refractory to antiarrhythmic drugs and DC cardioversion is difficult and still debated. We performed catheter ablation (CA) of sustained monomorphic ventricular tachycardias (VT) with high-energy DC shock (360-400 Joule) in 11 patients (pts) with incessant VT (duration greater than 24 h), refractory to antiarrhythmic drugs and DC cardioversion. Ten pts suffered from coronary disease and one pt from dilated cardiomyopathy. DC energy was delivered either at the site of the earliest endocardial activation (EEA) (six pts) or at the area of slow conduction (ASC) (five pts). In nine pts incessant VT could be terminated by DC ablation; two pts had to undergo emergency endocardial resection. During the mean follow-up of 31 +/- 26 (1-66) months nonfatal VT recurrences occurred in five pts with CA at the EEA and in one pt with CA at the ASC. We conclude that CA of incessant VT is an effective approach to terminate VT. However, there is a high incidence of nonfatal recurrence after CA, particularly when DC energy is delivered at the earliest site of endocardial activation.
对于抗心律失常药物和直流电复律难治的持续性室性心动过速(VT),其治疗困难且仍存在争议。我们对11例持续性VT(持续时间大于24小时)、对抗心律失常药物和直流电复律难治的患者,采用高能量直流电休克(360 - 400焦耳)进行持续性单形性室性心动过速的导管消融(CA)。10例患者患有冠心病,1例患有扩张型心肌病。直流电能量在最早的心内膜激动部位(EEA)(6例)或缓慢传导区域(ASC)(5例)释放。9例患者的持续性VT可通过直流电消融终止;2例患者不得不接受急诊心内膜切除术。在平均31±26(1 - 66)个月的随访期间,5例在EEA进行CA的患者和1例在ASC进行CA的患者发生了非致命性VT复发。我们得出结论,持续性VT的CA是终止VT的有效方法。然而,CA后非致命性复发的发生率很高,特别是当直流电能量在心内膜最早激动部位释放时。