Yuen Anthony Po-Wing, Ng Raymond Wai-Man, Lam Paul Kin-Yip, Ho Ambrose
Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong.
Head Neck. 2008 Feb;30(2):230-4. doi: 10.1002/hed.20678.
Tumor thickness of oral tongue carcinoma is an important independent prognostic factor for local recurrence, subclinical nodal metastasis, and survival. An accurate preoperative assessment of tumor thickness is therefore essential in optimizing treatment algorithm. The present study aims at evaluating the accuracy of intraoral ultrasonography in preoperative measurement of tumor thickness.
Forty-five patients with oral tongue carcinoma had intraoral ultrasonography to document tumor thickness using a 7.5 MHz right angle probe. The ultrasonic tumor thickness was correlated with the fresh unpreserved surgical specimen pathologic tumor thickness.
Ultrasonic tumor thickness had significant correlation with pathologic tumor thickness. The accuracies of ultrasonic measurement of tumor thickness in staging of tumor thickness at cutoff values between 3 and 15 mm were above 91%.
Intraoral ultrasonography had satisfactory accuracy in the measurement of tumor thickness and is a useful adjunct in assisting pretreatment staging and prognosis evaluation of oral tongue carcinoma.
口腔舌癌的肿瘤厚度是局部复发、亚临床淋巴结转移及生存的重要独立预后因素。因此，准确的术前肿瘤厚度评估对于优化治疗方案至关重要。本研究旨在评估口腔内超声在术前测量肿瘤厚度的准确性。
45例口腔舌癌患者使用7.5MHz直角探头进行口腔内超声检查以记录肿瘤厚度。将超声测量的肿瘤厚度与未保存的新鲜手术标本的病理肿瘤厚度进行相关性分析。
超声测量的肿瘤厚度与病理肿瘤厚度具有显著相关性。在肿瘤厚度截断值为3至15mm时，超声测量肿瘤厚度的分期准确率高于91%。
口腔内超声在测量肿瘤厚度方面具有令人满意的准确性，是辅助口腔舌癌术前分期及预后评估的有用手段。
