急性胰腺炎患者中与雷尼替丁相关的过敏反应：一例病例报告。
Anaphylactic reaction associated with Ranitidine in a patient with acute pancreatitis: a case report.
作者信息
Rethnam Ulfin, Yesupalan Rajam Sheeja
机构信息
Department of Orthopaedics, Glan Clwyd Hospital, Rhyl, UK.
出版信息
J Med Case Rep. 2007 Aug 31;1:75. doi: 10.1186/1752-1947-1-75.
UNLABELLED
: Ranitidine is a widely used drug and is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50 mgs of ranitidine and highlights this unusual but life threatening adverse reaction.
THE PATIENT
A 56 year old female with acute pancreatitis and a known allergy to metronidazole and buscopan developed an anaphylaxis few minutes following the injection of ranitidine for epigastric discomfort. She went on to develop anaphylactic shock and a cardiorespiratory arrest.
MANAGEMENT
She was managed with adrenaline, hydrocortisone and ventilatory support following which she had a full recovery.
CONCLUSION
Awareness of this rare but life threatening adverse reaction to a commonly used drug can avoid being caught unaware.
未贴标签
雷尼替丁是一种广泛使用的药物，已知耐受性良好。本病例报告阐述了单次静脉注射50毫克雷尼替丁后发生的严重过敏反应，并强调了这种罕见但危及生命的不良反应。
患者
一名56岁女性，患有急性胰腺炎，已知对甲硝唑和东莨菪碱过敏，在注射雷尼替丁治疗上腹部不适几分钟后发生过敏反应。她继而发展为过敏性休克和心肺骤停。
治疗
给予肾上腺素、氢化可的松和通气支持治疗后，她完全康复。
结论
认识到这种对常用药物罕见但危及生命的不良反应可以避免措手不及。
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