Sripriya R, Kumar V R Hemanth, Prabhu Rajesh, Ravishankar M
Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College and Research Institute, Puducherry, India.
J Nat Sci Biol Med. 2013 Jan;4(1):257-9. doi: 10.4103/0976-9668.107321.
Ranitidine, a widely used drug, is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50 mg ranitidine during the emergency cesarean section under spinal anesthesia. Anaphylaxis was successfully managed with Inj. adrenaline, Inj. hydrocortisone, ventilatory, and inotropic support following which she had a full recovery. Awareness of this rare but fatal adverse reaction to this commonly used drug could help in early recognition of the event if faced suddenly.
雷尼替丁是一种广泛使用的药物，已知耐受性良好。本病例报告描述了在脊髓麻醉下进行急诊剖宫产手术期间，单次静脉注射50毫克雷尼替丁后发生的严重过敏反应。通过注射肾上腺素、氢化可的松、通气支持和强心支持成功处理了过敏反应，之后患者完全康复。认识到这种常用药物罕见但致命的不良反应，有助于在突然遇到此类情况时尽早识别。
