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[脊柱硬膜外脓肿的非手术治疗:1例报告]

[Non-surgical treatment of spinal epidural abscesses: report of one case].

作者信息

Lin C C, Chi C S, Chen Y C, Lii Y P

机构信息

Department of Pediatrics, Veterans General Hospital, Taichung, Taiwan, R.O.C.

出版信息

Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1991 Sep-Oct;32(5):325-9.

PMID:1776463
Abstract

Spinal epidural abscesses (SEA) are uncommon in children. This paper reported a two-year-old boy who was noted to have neck stiffness, with local tenderness posteriorly. Bacterial meningitis was suspected initially in terms of the finding of the cerebral spinal fluid; antibiotics were prescribed. Three days later another spinal tap was performed because of persistent high fever and irritability. A pus-like material drained out as the needle punctured into the spinal region. A magnetic resonance image (MRI) scan of the spine revealed a SEA, with extensive involvement from the second cervical spine to the lumbosacral spine region. Culture of the pus, as well as the blood and CSF, were positive for Staphylococcus aureus. Because of extensive involvement of the spinal epidural space, the patient was again given antibiotics: Prostaphllin and Amikin intravenously for six weeks instead of laminectomy. Then the oral antibiotic (Keflex) was given to the patient for another three months after the boy was discharged from the hospital. A review of the literature shows the incidence of SEA to be increasing and the bacterial spectra to be broadening because of increasing use of immunosuppressing drugs or antibiotics, and the increase in numbers of immunecompromised patient. The clinical symptoms and signs of the SEA were non-specific, but SEA can be early diagnosed by computurized tomography (CT) scan or MRI scan with caution. The literature suggests that, if the patient's condition fits the criteria for non-surgical treatment, antibiotic therapy is the first choice for preventing the complication of spinal deformity, especially in children.

摘要

小儿脊髓硬膜外脓肿(SEA)并不常见。本文报道了一名两岁男孩,该男孩被发现颈部僵硬,后部有局部压痛。根据脑脊液检查结果,最初怀疑为细菌性脑膜炎,并使用了抗生素。三天后,由于持续高烧和烦躁不安,再次进行了脊髓穿刺。当针头刺入脊柱区域时,流出了一种脓性物质。脊柱磁共振成像(MRI)扫描显示为脊髓硬膜外脓肿,从第二颈椎到腰骶部脊柱区域广泛受累。脓液、血液和脑脊液培养均显示金黄色葡萄球菌阳性。由于脊髓硬膜外腔广泛受累,患者再次接受抗生素治疗:静脉注射苯唑西林和丁胺卡那霉素六周,而非进行椎板切除术。男孩出院后,又口服抗生素(头孢氨苄)三个月。文献综述表明,由于免疫抑制药物或抗生素的使用增加以及免疫功能低下患者数量的增加,脊髓硬膜外脓肿的发病率在上升,细菌谱也在变广。脊髓硬膜外脓肿的临床症状和体征不具有特异性,但通过计算机断层扫描(CT)或MRI扫描可谨慎地早期诊断。文献表明,如果患者的病情符合非手术治疗标准,抗生素治疗是预防脊柱畸形并发症的首选,尤其是在儿童中。

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