Henze Darrell A, Buzsáki György
Merck Research Laboratories, West Point, PA 19486, USA.
Prog Brain Res. 2007;163:199-216. doi: 10.1016/S0079-6123(07)63012-X.
Network oscillations are proposed to provide the framework for the ongoing neural computations of the brain. Thus, an important aspect of understanding the functional roles of various cell classes in the brain is to understand the relationship of cellular activity to the ongoing oscillations. While many studies have characterized the firing properties of cells in the hippocampal network including granule cells, pyramidal cells and interneurons, information about the activity of dentate mossy cells in the intact brain is scant. Here we review the currently available information and describe biophysical properties and network-related firing patterns of mossy cells in vivo. These new observations will assist in the extracellular identification of this unique cell type and help elucidate their functional role in behaving animals.
网络振荡被认为为大脑正在进行的神经计算提供了框架。因此，理解大脑中各种细胞类型的功能作用的一个重要方面是理解细胞活动与正在进行的振荡之间的关系。虽然许多研究已经描述了海马体网络中包括颗粒细胞、锥体细胞和中间神经元在内的细胞的放电特性，但关于完整大脑中齿状苔藓细胞活动的信息却很少。在这里，我们回顾当前可用的信息，并描述体内苔藓细胞的生物物理特性和与网络相关的放电模式。这些新的观察结果将有助于在细胞外识别这种独特的细胞类型，并有助于阐明它们在行为动物中的功能作用。
