Blaabjerg Morten, Zimmer Jens
Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winslowparken 21, DK-5000 Odense C, Denmark.
Prog Brain Res. 2007;163:85-107. doi: 10.1016/S0079-6123(07)63005-2.
Hippocampal mossy fibers are the axons of the dentate granule cells and project to hippocampal CA3 pyramidal cells and mossy cells of the dentate hilus (CA4) as well as a number of interneurons in the two areas. Besides their role in hippocampal function, studies of which are still evolving and taking interesting turns, the mossy fibers display a number of unique features with regard to axonal projections, terminal structures and synaptic contacts, development and variations among species and strains, as well as to normal occurring and lesion-induced plasticity and neural transplantation. These features are the topic of this review, which will use the mossy fiber system of the rat as basis and reference in its aim to provide an up-to-date, yet historically based guide to students in the field.
海马苔藓纤维是齿状颗粒细胞的轴突，投射至海马CA3锥体细胞、齿状回门区（CA4）的苔藓细胞以及这两个区域的一些中间神经元。除了在海马功能中发挥作用（对此的研究仍在不断发展且出现了有趣的转变），苔藓纤维在轴突投射、终末结构和突触联系、物种和品系间的发育与变异，以及正常发生的和损伤诱导的可塑性和神经移植方面表现出许多独特特征。这些特征是本综述的主题，本综述将以大鼠的苔藓纤维系统为基础和参考，旨在为该领域的学生提供一份基于历史且与时俱进的指南。
