Oladipo O O, Afolabi B B, Okorodudu A O
Department of Clinical Pathology, College of Medicine, University of Lagos.
Niger Postgrad Med J. 2007 Sep;14(3):213-6.
To measure the ultrafiltrable and total plasma calcium in normal pregnancy and pregnancies complicated with hypertension and pre-eclampsia.
Total and ultrafiltrable calcium concentrations were measured in maternal plasma from non-pregnant (35), normal pregnant (35), Pregnancy induced hypertension (35) and pre-eclamptic (20) women. Plasma total calcium level was measured by the o'cresolphthalein method. Ultrafiltrate of plasma was obtained using the Amicon MPS-1 micro-partition device.
There was no significant difference in the plasma total calcium level between the non- pregnant group and the pregnant group (normal, hypertensive and pre-eclamptic). However there was a significant reduction in the ultrafiltrable (protein free and complexed) calcium level in the pregnant group compared to the non-pregnant group (1.15mmol/L +/- 0.23 Vs 1.25mmol/L +/- 0.13) p<0.05.
Measurement of the ultrafiltrable calcium in addition to total calcium assay may be more useful in assessing calcium status in normal and complicated pregnancies.
测定正常妊娠以及合并高血压和子痫前期妊娠中的可超滤血浆钙和总血浆钙。
测定了非妊娠（35例）、正常妊娠（35例）、妊娠高血压（35例）和子痫前期（20例）女性母体血浆中的总钙和可超滤钙浓度。血浆总钙水平采用邻甲酚酞法测定。使用密理博MPS-1微型分离装置获得血浆超滤液。
非妊娠组与妊娠组（正常、高血压和子痫前期）之间的血浆总钙水平无显著差异。然而，与非妊娠组相比，妊娠组中可超滤（无蛋白和复合）钙水平显著降低（1.15mmol/L±0.23对1.25mmol/L±0.13），p<0.05。
除总钙测定外，测定可超滤钙可能对评估正常和复杂妊娠中的钙状态更有用。
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