Duse M, Caminiti S, Zicari A M
Department of Pediatrics, University La Sapienza, Rome, Italy.
Pediatr Allergy Immunol. 2007 Nov;18 Suppl 18:71-4. doi: 10.1111/j.1399-3038.2007.00639.x.
Risk factors of recurrent sinusitis involve upper respiratory infections, bacterial load of the adenoids, day care attendance and exposure to tobacco smoke as well as sinonasal abnormalities, including septal deviation, choanal atresia, polyps and hypoplasia of sinuses. Furthermore, several systemic disorders can facilitate the development of chronic sinusitis, such as allergic rhinitis, gastro-esophageal reflux disease (GER), cystic fibrosis, primary ciliary dyskinesia, and immunodeficiency diseases. A clinical practice guideline for the management of sinusitis is available only for the acute disease, but does not include for the management of the chronic form (i.e. chronic/recurrent sinusitis) and even less for the prevention strategies. As several studies indicate that the majority of children respond to sequential medical followed by surgical interventions, when needed, the best prevention of recurrence or chronicity is to properly treat acute sinusitis; in addition, children should be removed from larger and crowded day care whenever possible and should not be exposed to cigarette smoke. If allergic rhinitis co-exists, it can be managed with nasal steroids sprays and anti-histamines, although the long-term results are controversial. In case of chronic sinusitis, the strategy of prevention is to assess and to cure the associated conditions.
复发性鼻窦炎的危险因素包括上呼吸道感染、腺样体的细菌负荷、日托 attendance 和接触烟草烟雾,以及鼻窦异常,包括鼻中隔偏曲、后鼻孔闭锁、息肉和鼻窦发育不全。此外,一些全身性疾病可促使慢性鼻窦炎的发生,如过敏性鼻炎、胃食管反流病(GER)、囊性纤维化、原发性纤毛运动障碍和免疫缺陷疾病。目前仅有关于鼻窦炎急性病管理的临床实践指南,而不包括慢性形式(即慢性/复发性鼻窦炎)的管理,更没有预防策略。由于多项研究表明,大多数儿童在必要时对序贯药物治疗后再进行手术干预有反应,因此预防复发或慢性化的最佳方法是正确治疗急性鼻窦炎;此外,应尽可能让儿童离开规模较大且拥挤的日托机构,且不应使其接触香烟烟雾。如果同时存在过敏性鼻炎,可使用鼻用类固醇喷雾剂和抗组胺药进行治疗,尽管长期效果存在争议。对于慢性鼻窦炎,预防策略是评估并治愈相关疾病。