Xiao Yi, Tian Jian-Ming, Gong Jing, Yuan Xiao-Dong, Li Xiao-Ming, Sheng Jing, Yuan Min, Wang Min-Jie
Department of Radiology, Shanghai Changhai Hospital, Shanghai 200433, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2007 Jun;41 Suppl:134-7.
To evaluate the screening for consecutive patient population with suspected Coronary atherosclerotic heart disease (CAD) by noninvasive 64-slice computed tomographic coronary angiography.
2082 consecutive symptomatic subjects (1218 males, 868 female, with, mean age of 58.2 years old) with suspected CAD underwent MSCT studies. And 218 patients underwent coronary angiography within 7 days. Invasive coronary angiography was taken as golden standard for calculations of diagnostic accuracy.
Of 2082 subjects, 2063 (99.1%) were assessable, the mean examination duration was 4 minutes. Compared with CAG, the sensitivity of CTA to diagnose significant stenosis was 97.4%, specificity 90.1%, positive predictive value (PPV) 91.8% and negative predictive value (NPV) 96.8%.
Sixty-four-MSCT is accurate, convenient, noninvasive, safe means to coronary angiography with economic benefit. Thus, it can be considered as a valuable noninvasive screening technique.
通过无创64层计算机断层扫描冠状动脉造影术评估对连续的疑似冠状动脉粥样硬化性心脏病（CAD）患者群体的筛查情况。
2082例连续的有症状且疑似CAD的受试者（1218例男性，868例女性，平均年龄58.2岁）接受了多层螺旋CT（MSCT）检查。其中218例患者在7天内接受了冠状动脉造影。以有创冠状动脉造影作为计算诊断准确性的金标准。
在2082例受试者中，2063例（99.1%）可进行评估，平均检查时长为4分钟。与冠状动脉造影（CAG）相比，CTA诊断显著狭窄的敏感性为97.4%，特异性为90.1%，阳性预测值（PPV）为91.8%，阴性预测值（NPV）为96.8%。
64层MSCT是一种准确、便捷、无创、安全且具有经济效益的冠状动脉造影方法。因此，它可被视为一种有价值的无创筛查技术。
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