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[Introduction of aminoalkyl groups into prepared synthetic oligodeoxyribonucleotides by transamination of cytosine residues].

作者信息

Karpyshev N N, Bondarenko T Iu, Vtorushina I A, Kipriianov S M

出版信息

Bioorg Khim. 1991 Jun;17(6):809-12.

PMID:1776965
Abstract

The bisulphite-catalysed transamination of cytosine residues by means of ethylenediamine generally used for the natural nucleic acids modification has been extended on relatively short synthetic oligonucleotides. One of the aminoalkyloligonucleotides thus obtained has been used for preparing a biotinylated hybridisation probe.

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